Motorola WIRELESS TELEPHONE User Manual download pdf (Page 35)

18 add’l safety info

of the nerve sheath). No statistically signiﬁcant association

was found between mobile phone use and acoustic

neuroma. There was also no association between mobile

phone use and gliomas when all types of types of gliomas

were considered together. It should be noted that the

average length of mobile phone exposure in this study was

less than three years.

When 20 types of glioma were considered separately,

however, an association was found between mobile phone

use and one rare type of glioma, neuroepithelliomatous

tumors. It is possible with multiple comparisons of the same

sample that this association occurred by chance. Moreover,

the risk did not increase with how often the mobile phone

was used, or the length of the calls. In fact, the risk actually

decreased with cumulative hours of mobile phone use. Most

cancer causing agents increase risk with increased exposure.

An ongoing study of brain cancers by the National Cancer

Institute is expected to bear on the accuracy and repeatability

of these results.

b Researchers conducted a large battery of laboratory tests to

assess the effects of exposure to mobile phone RF on genetic

material. These included tests for several kinds of

abnormalities, including mutations, chromosomal

aberrations, DNA strand breaks, and structural changes in the

genetic material of blood cells called lymphocytes. None of

the tests showed any effect of the RF except for the

micronucleus assay, which detects structural effects on the

genetic material. The cells in this assay showed changes after

exposure to simulated cell phone radiation, but only after 24

hours of exposure. It is possible that exposing the test cells to

radiation for this long resulted in heating. Since this assay is

known to be sensitive to heating, heat alone could have

caused the abnormalities to occur. The data already in the

literature on the response of the micronucleus assay to RF are

conﬂicting. Thus, follow-up research is necessary.

FDA is currently working with government, industry, and

academic groups to ensure the proper follow-up to these

industry-funded research ﬁndings. Collaboration with the

Cellular Telecommunications Industry Association (CTIA) in

18 add’l safety info

particular is expected to lead to FDA providing research

recommendations and scientiﬁc oversight of new CTIA-

funded research based on such recommendations.

Two other studies of interest have been reported recently in the

literature:

a Two groups of 18 people were exposed to simulated mobile

phone signals under laboratory conditions while they

performed cognitive function tests. There were no changes in

the subjects' ability to recall words, numbers, or pictures, or

in their spatial memory, but they were able to make choices

more quickly in one visual test when they were exposed to

simulated mobile phone signals. This was the only change

noted among more than 20 variables compared.

b In a study of 209 brain tumor cases and 425 matched

controls, there was no increased risk of brain tumors

associated with mobile phone use. When tumors did exist in

certain locations, however, they were more likely to be on the

side of the head where the mobile phone was used.

Because this occurred in only a small number of cases, the

increased likelihood was too small to be statistically

signiﬁcant.

In summary, we do not have enough information at this point to

assure the public that there are, or are not, any low incident

health problems associated with use of mobile phones. FDA

continues to work with all parties, including other federal

agencies and industry, to assure that research is undertaken to

provide the necessary answers to the outstanding questions

about the safety of mobile phones.

What is known about cases of human cancer

that have been reported in users of hand-held

mobile phones?

Some people who have used mobile phones have been

diagnosed with brain cancer. But it is important to understand

that this type of cancer also occurs among people who have not

used mobile phones. In fact, brain cancer occurs in the U.S.

population at a rate of about 6 new cases per 100,000 people

each year. At that rate, assuming 80 million users of mobile

phones (a number increasing at a rate of about 1 million per

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